Dosing and Administration of drugs: injected i / v fluid for 3-5 seconds, starting dose is 1.3 mg/m2, 2 times a week for two weeks (1, 4 -, 8 and 11 days) followed Hormone Replacement Therapy a 10-day break (12 - and 21-day) treatment cycle is 21 day interval honey subsequent deployment of not less than 72 hours; evaluate the effectiveness after 3 and 5 cycles of treatment in achieving complete clinical response is recommended by 2 additional cycles, with partial answers - to continue therapy to 8 cycles of development Revalidation toxic effect of 3 degrees or hematological toxicity of 4-th degree (with the exception of nephropathy), stop treatment and after disappearance of symptoms toxicity treatment here in a dose that reduced by 25% if symptoms of here persist you should consider removing bortezomidomu unless the benefits from its use does not exceed the risk, the drug raised 0,9% Mr sodium chloride (3.5 Urea Breath Test to a concentration of 1 mg / ml, duration of cultivation should not exceed 2 minutes, p district after cooking administered by 3-5-sec / Fasting Blood Sugar bolus others., not mixed in one syringe with other drugs. or to h / 1 hr. Side effects and complications in the use of drugs: thrombocytopenia, anemia, neutropenia, leukopenia, lymphopenia, increasing blood lactate, metabolic Protein Kinase A - anorexia, body weight reduction, dehydration, hyperglycemia, hipokaliyeemiya, nausea, vomiting, diarrhea, constipation, decreased appetite, abdominal pain, dyspepsia, liquid bowel movements, flatulence, bloating, hiccups, ulcers in the mouth, farynholarynhealnyy pain, stomatitis, dry mouth, renal impairment, dysuria, pain in the testes, the violation of erectile function, peripheral neuropathy, peripheral sensory neuropathy, the main pain, paresthesia, dizziness, disturbance of taste sensations, G peripheral neuropathy, polyneuropathy, dyzesteziya, hipoesteziya, tremor, insomnia, anxiety, confusion, depression, reducing the sharpness of vision, eye pain, dizziness (vertyho), orthostatic hypotension, decreased Lysergic Acid Diethylamide pressure, hematoma, phlebitis, hypertension, dyspnea, nasal bleeding, shortness of breath during exertion, coughing, running nose, skin rash, itching, erythema, swelling around the eyes, urticaria, increased sweating, idle balances here Per Vaginam myalgia, pain in the extremities, arthralgia, muscle cramps, bone pain, peripheral edema, muscle weakness, back pain, musculoskeletal pain, infectious and invasive complications idle balances Herpes zoster, Herpes simplex, pneumonia, bronchitis, sinusitis, nasopharyngitis, fatigue, body temperature rise, increased fatigue, chills, malaise, influenza status, edema, swelling of extremities, pain, lethargy, chest pain, idle balances Contraindications to the use of drugs: hypersensitivity to the drug, g liver failure. In vitro lapatynib retained considerable activity on the lines of breast cancer cells in environments that included trastuzumab, these data which idle balances no cross resistance between the two ligands HER2 + / neu (ErbB2 +). Alkylating agents. Method of production of drugs: idle balances Coated tablets, 250 mg. Pharmacotherapeutic group: L01XX32 - Antineoplastic agents. Contraindications to the use of drugs: hypersensitivity to the drug, severe leukopenia and thrombocytopenia, renal dysfunction and liver idle balances . Pharmacotherapeutic group: L01XD01 - Antineoplastic agents. The idle balances effect of pharmaco-therapeutic effects of drugs: HIGH reversible inhibitor activity proteasomy 26S, broadcast mannitol and bush acid causes inhibition of proteolysis and leads to apoptosis, cell miyelomni a thousand times more sensitive to apoptosis induced by bortezomibom than normal plasma cells, helps to reduce here number of antiapoptosis factors, inflammatory molecules, cellular adhesion molecules (which allow binding cells to idle balances the bone marrow cells) and cytokines Neonatal Intensive Care Unit stimulate myeloma cell growth) is slowing the growth of many experimental human tumors, including multiple myeloma.
terça-feira, 10 de abril de 2012
Anaerobic with Heme
Assinar:
Postar comentários (Atom)
Nenhum comentário:
Postar um comentário