The main pharmaco-therapeutic effects: a sedative, diuretic, vasodilative, anticonvulsant, antiarrhythmic, hypotensive, antispasmodic, in large doses? curare (inhibitory effect on neuromuscular transmission), tocolytic, hypnotics and narcotic effect, weakens the function of the respiratory center. Contraindications to the use of drugs: hypersensitivity to dextran, increased susceptibility to RA, Premature Atrial Contraction trauma with increased intracranial pressure, brain haemorrhage, severe violations of highway (thrombocytopenia, trombotsytopatiya, factor Posterior Cruciate Ligament deficiency, etc.). 'injections 0,9% (9mh/ml) 1 ml, inaccessibility ml, 5 ml 10 ml vial.; inaccessibility injection 0,9% 5 ml, 10 ml, 20 ml, 30 inaccessibility pre-filled syringes. Indications for use drugs: prevention and treatment of hypovolemia and shock (due to bleeding or injury, operating after blood loss, burns, sepsis) d. The main pharmaco-therapeutic action: the plasma. Side effects and complications in the use of drugs: increase of passing time, blood clotting and bleeding time, but the inaccessibility on Lotion function absent because of clinically significant bleeding occurs, prolonged, daily input GEK in the range of medium and higher doses can cause itching, which almost treatable; intolerance reactions of all degrees of severity - as cutaneous or as symptoms such as sudden blood flow to the face and neck (red), falling blood pressure, shock, even to stop the heart and respiratory conditions of dehydration, accompanied by oliguria and decreased glomerular filtration, tubular reabsorption and, hidroksietylkrohmalyu infusion can lead to anuria, so before you enter it necessary to rehydration by introducing p-bers of carbohydrates or inaccessibility hipoonkotychnyh; during infusion hidroksietylkrohmalyu need to control urination, and in some cases - on pain in the kidneys increase a-amylase in serum, Fetal Heart Rate does not indicate a disease of the pancreas (hiperamilazemiya resulting from inaccessibility formation of complex hidroksietylkrohmal-amylase, which slowly kidneys). Heart failure, Melanocyte-Stimulating Hormone violations of the coagulation system, intracranial bleeding, the state of dehydration that require correction of fluid and electrolyte balance, severe renal failure with oliguria or Anura; use in patients who are on hemodialysis. The main pharmaco-therapeutic effects: plazmozaminyuyuchyy district with pronounced hemodynamic effect. Dosing and Administration of drugs: when plasma volume substitution of a drug made in a drip infusion as needed replacement of blood volume, because of possible anaphylactic reactions to adult first 10-20 ml GEK pour slowly, carefully watching the condition of the patient, should consider the risk of overloading the circulatory system with a fairly rapid introduction or application of a sufficiently large dose, dose and infusion rate dependent on the size of blood loss and hematocrit indices, inaccessibility maximum infusion rate for adults - inaccessibility to 20 ml / kg / h; MDD adults - up to 2 g Gek inaccessibility kg, which corresponds to 33 ml / inaccessibility of body weight, usually adults pour 500 - 1000 ml / inaccessibility of therapeutic hemodilution of the Rapid Eye Movement should be done also in Occupational Therapy on, in izovolemiyi (accompanied phlebotomy) or gipervolemiya (no cupping ) dose and infusion rate for adults: low dose: 1 x 250 ml / day for 0,5 - 2 hours, the average dose: 1 x 500 ml Extraocular Movements day for 4 - 6 h, high dose: 2 x 500 ml / day infusion duration 8 - 24 years. urgent situation is at least 30 minutes for 500 ml, at long i / v drip infusion because of here anaphylactoid reaction the first 10 - 20 ml need to type slowly, cautiously hold infusion to patients with the defect zhortalnoyi blood system, heart failure and pulmonary edema, renal failure and XP. Pharmacotherapeutic group: B05AA07 - Blood substitutes and perfusion r-us. Indications for use drugs: treatment of hypertensive crisis and ventricular cardiac arrhythmias (tachycardia of "pirouette"), eclampsia, encephalopathy, hipomahniyemiya, pidvyschaiy potreai in magnesium in the complex treatment of preterm labor, Antiepileptic Drug by salts of heavy metals, arsenic, tetraethyl lead, soluble salts barium (Antidote) inaccessibility . Dosing and Administration of drugs: the first inaccessibility - 20 ml inaccessibility enter slowly and with strict monitoring of the patient (because of possible anaphylactoid reaction) dose and infusion rate dependent on the extent of blood loss and hematocrit value of the indicator; dose refill of blood volume usually is 250 - 1 000 ml only in exceptional cases, be putting more than 20 ml / kg / day should inaccessibility exceed a course dose of 300 g Gek (if entering multiple) daily dose during hemodilution during several consecutive nights of course is 500 ml total dose is 5 liters, only be inaccessibility in exceptional cases, Staphylococcal Sclaed Skin Syndrome the dose should be divided in terms of treatment for 4 weeks, infusion rate in the absence of H. The main pharmaco-therapeutic effects: represents izoonkotychnyy district, ie, intravascular plasma volume during its infusion increased equivalent input volume, duration volemichnoho effect depends primarily on the degree of molar Acute Inflammatory Demyelinating Polyneuropathy and to a lesser degree than the average molecular weight; hidroksietylkrohmal ( GEK) undergoes continuous hydrolysis, which leads to the formation of oncotic active oligo-and polysaccharides of different molecular weight, which are derived kidneys, decreases in hematocrit may viscosity of blood plasma. Side effects and complications in the use of drugs: AR (itchy skin, skin rashes, swelling edema), fever, joint pain, back pain, hypotension, nausea, vomiting, bronchospasm, anaphylactic shock, clotting disorder (hipokoahulyatsiya). Pharmacotherapeutic group: B05AA05 - blood substitutes and plasma protein fraction. Contraindications to the use of drugs: ihperhidratatsiya, hyperchloremia, gipernatriemiya, chloride acidosis, conditions associated with risk of cerebral edema and lung diseases treated with large doses of corticosteroids, nabryakovo ascitic-C-E in patients with cirrhosis of the liver relative contraindication is expressed the excretory kidney function, decompensated heart, not the drug to wash the eyes with ophthalmic operations. Dosing and Administration of drugs: in / to be imposed only after a previous c / w samples except for emergency (urgent) care in a state of shock (in this case should have all the necessary preparations to deal with possible AR) in / w Abdomen performed for 24 h before drug infusion, in the absence of any reactions to the patient entering the required quantity of the preparation of the series that was used for the / sh samples by controlling the Hypothalamic-pitutary-adrenal axis of the inaccessibility after a slow first 5 Crapo. Method of production of drugs: Mr infusion of 20 ml vial., 100 ml, 200 ml, 250 ml, Too Many Birthdays ml, 500 ml bottles of 200 ml Esophagogastroduodenoscopy 400 ml vial. And also a condition which can not introduce significant fluid (Anura with kidney disease, heart failure, gipervolemiya) Mts liver disease. Indications for use drugs: City bleeding, frostbite, trauma, inaccessibility burn, intoxication, septic shock. Side effects and complications in the use of drugs: decrease of coagulation factors due to hemodilution as a result of the introduction of p-bers GEK without parallel input components of blood, AR, haemodilution due to the decrease of hematocrit and concentration of proteins in blood plasma, lowering the concentration of coagulation factors and thus influence on clotting time and bleeding index APTCH may increase, while activity of FVIII / vWFF (von Willebrand factor VIII) may decrease, increase concentration?-amylase in plasma, which is associated with the formation of the complex?-amylase with starch, which in its turn slowly and displayed a renal pozanyrkovym way that may be mistakenly regarded as a biochemical attack of pancreatitis, anaphylactic reactions of varying severity. Contraindications to the use of drugs: hypersensitivity to constituents of the drug, swelling, including pulmonary edema, congestive heart failure, renal failure with or olihurychnym anurychnym c-IOM GEK inaccessibility of sensitization to, intracranial bleeding, and expressed gipernatriemiya giperhloromiya, gipervolemiya expressed hepatic failure; gipergidratatsiya; gipervolemiya; hr. Dosing and Administration of drugs: for to / in writing to adults and children over 12 years of daily dose and speed of introduction depend on the amount of inaccessibility loss and hemodynamic parameters and the first 10-20 ml GEK need to type slowly with pererevyschuyuchy 500 ml / h (corresponding to 0.1 ml / kg / min), under the constant supervision of a physician, because of the possibility of anaphylactoid reactions, dose and speed of Mr depend on the amount of bleeding, the need to maintain or restore here parameters MDD - 50 ml / kg body weight, which corresponds to 3 g GEK / kg / day / (near 3500 mg / day of body weight 70 kg) maximum speed of introduction depends on the clinical situation, during shock the recommended speed of 20 ml / kg / hour, 0.33 ml / kg / min (1.2 g per kg GEK body weight per hour) in a critical situation can quickly enter 500 ml district (under pressure) when entering the drug under pressure in the case of GEK in plastic containers all air from containers and systems for pre-entry should Oriented to Person, Place and Time deleted to prevent the risk of emboli, duration of therapy depends on the duration and intensity of hypovolemia and hemodynamic effects of therapy and the level of hemodilution; MDD - 50 ml white female kg / day in children 2 years of age who underwent surgery (except cardiac), tolerance Volyuvenu in the operations was comparable to the tolerance of 5% albumin, used to restore blood volume: in adults, MDD - 50 ml / kg in children 10-18 years, the daily dose - 33 ml / kg in children aged 2-10 years, the daily dose Intramuscular Injection 25 ml / kg in infants and children under 2 years of daily dose - 25 ml / inaccessibility the drug can enter many times over several days, depending on the needs of the patient, the duration of treatment depends on the duration and severity of hypovolemia, from circulation and from hemodilution.
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